Driving an E-Series Van is somewhat like piloting a big SUV, only there is a bit more rear overhang. Ford has done a good job making sure that certain aspects...
... of the E-Series are not as gargantuan as the rest of the vehicle, such as placing the door handles down low so you don't have to reach up to operate them.
In a nod to better visibility, the lower edge of the side glass extends far down the van's side, giving the passengers a good view in all directions and allowing the driver to see objects that might not appear in the sideview mirrors. The steering is moderately dampened to give the driver some sense of the road, and the ride is fairly smooth when the vehicle is fully loaded.